96-03-21 Volunteers Sought For Study of Stress Effects on Health VOLUNTEERS SOUGHT FOR STUDY OF STRESS EFFECTS ON HEALTH COLUMBUS -- Ohio State University researchers are working to understand how stress affects people's health. They are seeking volunteers to participate in a study of how every-day types of challenges affect cholesterol, heart rate, blood pressure, and related measures. The study is being conducted by Catherine Stoney, director of the Cardiovascular Behavioral Medicine Laboratory and associate professor of psychology; and Karen M. Cook, research assistant. According to Stoney, studies have demonstrated that both chronic and acute stress result in significant increases in total cholesterol, low density lipoprotein-cholesterol and triglyceride concentrations in healthy, middle-aged people. "These findings are important because we know that high levels of these fats in the blood increase risk for heart disease," Stoney said. "Other studies from the laboratory have also shown that some individuals are better at coping with stress than are others; those that cope better tend to have lower cholesterol levels than those who do not cope well." "The aim of the program is to better understand the biologic and clinical importance of stress on the body," Cook said. "We are particularly interested in understanding how stress affects cholesterol and related risk factors for coronary heart disease." The researchers are looking for men and premenopausal women between 40- and 45-years old and men and women ages 55 to 60. Volunteers must be healthy non-smokers, who aren't using any medication that could affect their heart or cholesterol levels. Women must not be taking estrogen or other hormones. Each individual will participate in three separate two-hour sessions within a single week and will fast 12 hours prior to coming to the laboratory. Blood samples will be taken and participants will be asked to participate in some challenging tasks. Participants will be given a complete cholesterol profile and information on their heart rate, blood pressure and lean body mass. In addition, they will each receive up to $200, free parking, and, after each visit, a light breakfast or lunch. Volunteers can contact Stoney or Cook at (614) 292-0588, 688-3346, or 688-3895. The study is being funded by the National Heart, Lung and Blood Institute, an agency of the National Institutes of Health. # Contact: Karen M. Cook, (614) 688-3895. Written by Tom Spring. [Submitted by: Von Reid-Vargas (ereid@magnus.acs.ohio-state.edu) Thu, 21 Mar 1996 12:47:16 -0500] All documents are the responsibility of their originator.