Research at Ohio State

Research at Ohio State

Research saves lives

New medical treatments and scientific discoveries help Ohioans live longer, healthier, happier and more productive lives. This research would not be possible without support from our government partners.

A law enforcement official has his head examined for trauma

Helping law enforcement officers manage head trauma

A new study is the first to shed light on the high prevalence of head injuries, and related mental health symptoms, in a previously overlooked population when it comes to concussion surveillance: law enforcement officers.

The federal government, along with state and local governments, funds research that leads to life-saving discoveries, including new treatments and diagnoses for diseases like cancer, heart disease, Alzheimer’s, Parkinson’s and diabetes.

Crucial government funding supports Ohio State research that benefits farmers, teachers, soldiers, law enforcement officers, schoolchildren, medical patients and many more.

  • Nearly half of Ohio State’s $1.58 billion in annual research and development spending comes from federal agencies like the Department of Defense, National Institutes of Health, Department of Energy and National Science Foundation.
  • The state of Ohio sponsors an additional $67 million of leading-edge research.

Cancer research

A machine learning tool to diagnose, monitor colorectal cancer

New platform shows molecular differences with tumor presence, disease stage

Light-induced gene therapy disables cancer cells’ energy center

In study, targeted delivery shrinks brain, breast tumors in mice

Squaring off against a clever killer: breast cancer that extends to the brain

Ohio State researcher strives to improve outcomes for breast cancer patients with brain metastases

Revealing structural secrets of a key cancer protein

Study detects regions affected by dangerous mutations

Chronic diseases

A new ventilator-on-a-chip model to study lung damage

Device enables real-time detection of injury at cellular level

Generative AI on track to shape the future of drug design

Study finds model produces more potent drug candidates, could speed therapy development

Gene therapy relieves back pain, repairs damaged disc in mice

Study suggests nanocarriers loaded with DNA could replace opioids

Machine learning models rank predictive risks for Alzheimer’s disease

Study suggests genetic risk outweighs age in adults over 65

Mental health and addiction

Keto diet linked to reduced depression symptoms in college students

Study suggests well-formulated ketogenic diet is feasible add-on mental health therapy

$19.5M NIH grant to Ohio State funds suicide risk prediction research

Study aims to enhance suicide risk screening approaches, measure cognitive, sleep, mental health factors

A 37% drop in overdose deaths from drugs mixed with opioids — fentanyl included

Study campaigns expand to reach users of non-cocaine stimulants laced with fentanyl

Ohio State, state of Ohio launch $20 million ‘SOAR’ Study

Study will identify risk, resiliency factors to improve behavioral health outcomes

Public safety

Ohio State, Mount Carmel study treatment options for blood loss in trauma patients

DOD funds trial testing emergency treatment of people with severe injuries

In law enforcement, a link between head injuries and depression, PTSD

Study suggests 3 in 4 officers have experienced at least 1 concussion

Dept. of Defense awards Ohio State $8.4 million to study suicide prevention for military

Ohio State researchers have developed several strategies

Up to the challenge of improving intersection safety

An Intersection Safety System has been proposed with multisensor fusion, perception, AI, machine learning and active warning methodologies