Research at Ohio State
Research at Ohio State
Research saves lives
New medical treatments and scientific discoveries help Ohioans live longer, healthier, happier and more productive lives. This research would not be possible without support from our government partners.

Setting standards of care for brain injuries in first responders
Ohio State hosted the 1st International Conference on TBI in First Responders, where 60 experts convened to reach consensus on evidence-based guidelines for traumatic brain injury recognition and management and return to duty in law enforcement officers, corrections personnel, firefighters and emergency medical technicians.
The federal government, along with state and local governments, funds research that leads to life-saving discoveries, including new treatments and diagnoses for diseases like cancer, heart disease, Alzheimer’s, Parkinson’s and diabetes.
Crucial government funding supports Ohio State research that benefits farmers, teachers, soldiers, law enforcement officers, schoolchildren, medical patients and many more.
- Nearly half of Ohio State’s $1.68 billion in annual research and development spending comes from federal agencies like the Department of Defense, National Institutes of Health, Department of Energy and National Science Foundation.
- The state of Ohio sponsors an additional $67 million of leading-edge research.
Cancer research
Killing cancer cells with RNA therapeutics
In mouse study, RNA micelles shrink metastasized tumors in lungs
A machine learning tool to diagnose, monitor colorectal cancer
New platform shows molecular differences with tumor presence, disease stage
Best snapshots yet of DNA repair protein relevant to BRCA mutations
Detailed structural images may reveal ways to inhibit mutations that heighten the risk for cancer
Squaring off against a clever killer: breast cancer that extends to the brain
Ohio State researcher strives to improve outcomes for breast cancer patients with brain metastases
Chronic diseases
Researchers find increasing a type of protein helps slow heart failure
Novel gene therapy approach could lead to new treatments
Ohio State receives $7.7 million to study lung inflammation and injury
NIH funding bolsters research into the cause and treatment of acute respiratory distress syndrome
Risk for Lyme disease in Ohio is equal to Connecticut, study shows
Prevalence of infected ticks, hosts is comparable to endemic US regions
New technology enables ‘rewriting a chapter’ of the genome
Inserting a large segment of DNA into a genome shows potential to expand gene therapy treatment options
Mental health and addiction
Keto diet linked to reduced depression symptoms in college students
Study suggests well-formulated ketogenic diet is feasible add-on mental health therapy
$19.5M NIH grant to Ohio State funds suicide risk prediction research
Study aims to enhance suicide risk screening approaches, measure cognitive, sleep, mental health factors
A 37% drop in overdose deaths from drugs mixed with opioids — fentanyl included
Study campaigns expand to reach users of non-cocaine stimulants laced with fentanyl
Ohio State, state of Ohio launch $20 million ‘SOAR’ Study
Study will identify risk, resiliency factors to improve behavioral health outcomes
Public safety
Novel gene-based therapy helps nerves heal better after severe injury
Boosted blood vessel growth at injury sites improves healing outcomes
Study of influenza D in human cells, tissue hints at spillover potential
Results suggest need for investment in surveillance and understanding of flu D’s biology