Research at Ohio State

Research at Ohio State

Research saves lives

New medical treatments and scientific discoveries help Ohioans live longer, healthier, happier and more productive lives. This research would not be possible without support from our government partners.

Illustration of creation of extracellular vesicles

Red blood cells inspire next-generation therapeutic nanocarriers

Red blood cells serve as the foundation for nanocarriers that show promise in a new study as effective and efficient vehicles for gene therapy, tumor targeting and other medical treatments. Ohio State scientists combined engineering and nature to design tiny cargo-containing particles.

The federal government, along with state and local governments, funds research that leads to life-saving discoveries, including new treatments and diagnoses for diseases like cancer, heart disease, Alzheimer’s, Parkinson’s and diabetes.

Crucial government funding supports Ohio State research that benefits farmers, teachers, soldiers, law enforcement officers, schoolchildren, medical patients and many more.

  • Nearly half of Ohio State’s $1.68 billion in annual research and development spending comes from federal agencies like the Department of Defense, National Institutes of Health, Department of Energy and National Science Foundation.
  • The state of Ohio sponsors an additional $67 million of leading-edge research.

Cancer research

Killing cancer cells with RNA therapeutics

In mouse study, RNA micelles shrink metastasized tumors in lungs

A machine learning tool to diagnose, monitor colorectal cancer

New platform shows molecular differences with tumor presence, disease stage

Wearable electric-field device slows aggressive breast cancer in preclinical study

A wearable, drug-free approach reduced tumor growth and spread in preclinical models of triple-negative breast cancer 

Squaring off against a clever killer: breast cancer that extends to the brain

Ohio State researcher strives to improve outcomes for breast cancer patients with brain metastases

Chronic diseases

Tomato-soy juice lowers inflammation in adults with obesity

Study hints at potential for a ‘functional food’ that improves health

Ohio State receives $7.7 million to study lung inflammation and injury

NIH funding bolsters research into the cause and treatment of acute respiratory distress syndrome

Risk for Lyme disease in Ohio is equal to Connecticut, study shows

Prevalence of infected ticks, hosts is comparable to endemic US regions

Phase 1 clinical trial set to begin on first leishmaniasis vaccine

The disfiguring skin disease is common in tropical regions of the world and gaining ground in the United States

Mental health and addiction

Keto diet linked to reduced depression symptoms in college students

Study suggests well-formulated ketogenic diet is feasible add-on mental health therapy

$19.5M NIH grant to Ohio State funds suicide risk prediction research

Study aims to enhance suicide risk screening approaches, measure cognitive, sleep, mental health factors

A 37% drop in overdose deaths from drugs mixed with opioids — fentanyl included

Study campaigns expand to reach users of non-cocaine stimulants laced with fentanyl

Ohio State, state of Ohio launch $20 million ‘SOAR’ Study

Study will identify risk, resiliency factors to improve behavioral health outcomes

Public safety

Sweeping up dust to detect emerging viruses

54 distinct viruses detected in dust samples collected from schools, office buildings and residence halls

Ohio State leads $12 million national effort to improve emergency respiratory care

Study compares 2 oxygen delivery approaches

Ohio State studies treatment options for trauma patients with severe burns

Trial examines whether plasma early in the course of treatment helps patients survive their injuries

Ohio State researchers help reduce arsenic exposure from well water

Arsenic, which can pose significant health risks, is a common groundwater contaminant affecting private wells